منابع مشابه
Failing Human Hearts
Background A variety of previous studies have demonstrated reduced diastolic potential and electrical activity in atrial specimens from patients with heart disease. Although K' channels play a major role in determining resting membrane potential and repolarization of the action potential, little is known about the effects of preexisting heart disease on human atrial K' channel activity. Methods...
متن کاملFailing ageing hearts.
Chronic heart failure is a major and increasing cause of morbidity and mortality. Although it is widely recognized that chronic heart failure affects the elderly, little attention has been given to its study specifically in this patient group. For example, patients with chronic heart failure in clinical trials frequently have an average age of around 60 years, in comparison to one of nearer 80 ...
متن کاملOxidative capacity in failing hearts.
Although high-energy phosphate metabolism is abnormal in failing hearts [congestive heart failure (CHF)], it is unclear whether oxidative capacity is impaired. This study used the mitochondrial uncoupling agent 2,4-dinitrophenol (DNP) to determine whether reserve oxidative capacity exists during the high workload produced by catecholamine infusion in hypertrophied and failing hearts. Left ventr...
متن کاملWhy students fail calculus
Received doctrine that permeates the literature and practice of K-12 mathematics education, if implemented uncritically, will obstruct the development of skills that are critical for the study of calculus. Two false dichotomies are of principle concern : • Blind rote is always bad and leads to error, whereas thinking about what you are doing is always good and leads to success • Solving problem...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2017
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2017070797